CAS No.: | 118292-40-3 |
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Formula: | C21h21no2s |
EINECS: | / |
Type: | Pharmaceutical Intermediates |
Appearance: | Powder |
Quality: | Refined |
Samples: |
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Customization: |
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Name
|
Tazarotene
|
CAS No
|
118292-40-3
|
Appearance
|
White powder
|
Specification
|
99%
|
Molecular Formula
|
C21H21NO2S
|
Molecular Weight
|
351.46
|
EINECS
|
601-516-4
|
Tazarotene is most commonly used topically to treat acne, psoriasis (a skin disease in which red, scaly patches form on some areas of the body), and to reduce skin wrinkling and liver spots. Tazarotene is rated pregnancy category X, and should not be used by pregnant women. "There is limited evidence that tazarotene and isotretinoin benefit patients with moderate photodamage on the face: both are associated with skin irritation and erythema." In addition to tretinoin, which has been associated with greater skin improvements with high concentrations, tazarotene and isotretinoin creams are also found to be effective for photodamage, but at the expense of skin irritation. More evidence is needed before any recommendations can be made on oral or topical polysaccharides or hydroxy acids. Evidence from one trial suggests that the effectiveness of 0.05% tretinoin, is equivalent to the effects of 0.05% and 0.1% tazarotene. However, for acne vulgaris, several recent double blind studies have shown consistently superior efficacy for tazarotene and roughly equal tolerability for both treatments
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