Factory Offer 99% Purity Raw Material Paricalcitol Pharmaceutical Powder CAS No 131918-61-1 Paricalcitol
What is vitamin D Derivative Drugs?
Active vitamin D drugs are a general term for a series of vitamin D2/D3 derivatives, commonly referred to as "calciferol" drugs. These compounds are complex in structure and involve techniques such as photochemistry and microbial transformation. They are difficult to synthesize, sensitive to light and oxygen, and the API in the preparation is microgram-level, and the development threshold is high. Clinically used mainly for the treatment of osteoporosis, secondary hyperparathyroidism and psoriasis.
Description
Paricalcitol was launched as Zemplar in the US for the prevention and treatment of secondary hyperthyroidism associated with chronic renal failure. Paricalcitol is a synthetic vitamin D2, namely a novel 1-alpha-hydroxy-19-noranalogue in which the ring A exocyclic methylene group, typical of all vitamin D systems, has been replaced by two hydrogen atoms. Paricalcitol is the first vitamin D analogue marketed for this indication. In patients with chronic renal failure, Paricalcitol appreciably reduced levels of parathyroid hormone (PTH) without a significant difference in the incidence rate for hypercalcemia or hyperphosphatemia when compared with placebo.
| Product Name: |
Paricalcitol |
| Synonyms: |
PARICALCITOL (10 MG)F0E3030.997MG/MG(AI);
19-nor-1alpha,25-dihydroxyvitamin D2;(1R,3R)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(E,2R,5S)-6-Hydroxy-5,6-dimethylhept-3-en-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]cyclohexane-1,3-diol;
Zemplar; |
| CAS: |
131918-61-1 |
| Molecular Structure: |
|
| Appearance |
White or off-white powder |
| MF: |
C27H44O3 |
| MW: |
416.64 |
| EINECS: |
658-064-6 |
| Product Categories: |
Vitamin D3 analogs;Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals |
Function & Application
1) Synthetic analog of vitamin D. Antihyperparathyroid.
2) Antihyperparathyriod
3) 1,25-Dihydroxy vitamin D2 is a potent agonist of the vitamin D receptor. Paricalcitol is a synthetic 1,25-dihydroxy vitamin D2 analog. As vitamin D deficiency, associated with chronic kidney disease, leads to an increase in parathyroid hormone (secondary hyperparathyroidism), paricalcitol is used in renal patients to block parathyroid hormone overproduction. Vitamin D deficiency is also a risk factor in cancer, cardiovascular disease, hypertension, and diabetes, and paricalcitol may have applications in those contexts as well.
Function
It is used for the prevention and treatment of SHPT, and the prevention and treatment of SHPT in patients with stage III and IV chronic kidney disease (CKD) before dialysis and transplantation.
Packing & Delivery
To better ensure the safety of your goods, professional, environmentally friendly, convenient and efficient packaging services will be provided.
We will deliver the goods intact to you by express.
If you want to know the shipping cost, please send an inquiry with your address.
Hubei YYC Industrial Co., Ltd. is located in Wuhan Donghu High-Tech Economic Development Zone, specilize in production and exportation of pharmaceutical raw materials and intermediates, peptides, cosmetic ingredients, has invested and closed cooperated with domestic manufacturers and Laboratories from famous Universities to meet the different customers' needs from grams to tonnage quantity. We always stand in high starting, high stand and high quality, and masters strict management for production procedure and quality control. All the products must pass our quality test before being sending to customers. We have business with more than 60 countries, of which our main markets include Central and South America, Southeast Asia, Central Asia, Africa, Middle East, Eastern Europe, Russia and more and more higher regulative markets are being developed as long as our deep ploughing .
What services can we provide?
Accepted Delivery Terms: FOB, CIF, EXW, Express Delivery;
Accepted Payment Currency:USD,EUR,CAD,AUD,HKD,CNY;
Accepted Payment Type: T/T,MoneyGram,PayPal,Western Union,BTC;
Language Spoken: English, Chinese, Spanish, French, German, Portuguese, Russian.
1. We supply Peptides, APIs & Intermediates, Anti-hairloss, Oil, Food Additive and so on to satisfy your needs;
2. We will reply you for your inquiry in 24 hours;
3. Our Q&C team will inspect every product quality strictly before delivery;
4. After delivery, we will track the products for you once every two days, until you get the products. When you got the goods, if you have any questions about the problem, contact with us, we will offer the solve way for you.
Q1: What's your MOQ?
A:MOQ is 1KG.
Q2:How about delivery leadtime?
A:Delivery lead time: About 3-5 days after payment confirmed. (Chinese holiday not included)
Q3: Is there a discount?
A:Different quantity has different discount.
Q4:How to start orders or make payments?
A:Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T, Western Union or Bitcoin.
Q5: How do you treat quality complaint?
A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
Q6. We don't know you at all, how can we trust you?
A: You are always warm welcomed to visit us at any time.Before we start B2B, MIC has audited our company on-spot and approved our credit.Commitment is the No.1 Point of our Enterprise's Value.
Q7.Do you test all your goods before delivery?
A:Yes, we have 100% test before delivery,International Authorized Third-Party Test for the products if you need are highly welcomed.
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